CureZone.com
   Home > Article Index > Antiphospholipid Syndrome > Ailments, Disorders and Illness

• Go Back

Reprinted from:
http://www.reuters.com

Bacteria Promote Vessel Growth in Gut

November 05, 2002 10:32 AM ET

By Merritt McKinney

NEW YORK (Reuters Health) - Bacteria that live in the intestine play an essential role in the development of blood vessels in the gut, Missouri researchers report. When researchers at Washington University School of Medicine in St. Louis raised mice in a bacteria-free environment, blood vessels in the gut did not develop until the mice were exposed to bacteria.

In an interview with Reuters Health, senior author Dr. Jeffrey I. Gordon said, "Developmental processes, such as those that we have studied, are not the exclusive responsibility of the host," for example the mouse or human body. "Environmental factors, such as gut bacteria, play an important role," he said.

That the body contains bacteria, or flora, that are helpful is not a new idea, according to Gordon.

"We have this vast community of microbes that colonize from the moment of our birth," he said. Gordon added that these microbes "bring to us a great bunch of metabolic traits that we haven't developed."

Until this latest research, led by first author Dr. Thaddeus S. Stappenbeck, it was not known that bacteria were essential for forming blood vessels in the gut. The investigators made this discovery when they compared blood vessel growth in normal mice and mice that grew up without any bacteria in the small intestine.

The growth of blood vessels in the gut was not nearly as extensive in germ-free mice as in normal mice, the researchers report in the online early edition of the journal Proceedings of the National Academy of Sciences. But normal vessel development was restored 10 days after the researchers colonized the germ-free mice with bacteria called Bacteroides thetaiotaomicron.

Next, Gordon and his colleagues discovered that antibacterial intestinal cells called Paneth cells interact with bacteria to promote the growth of blood vessels. When they genetically engineered mice to lack Paneth cells, blood vessel growth was much less extensive.

The next step, Gordon said in the interview, is to "recreate and dissect out the pathway by which bacteria are able to stimulate angiogenesis," or the formation of new blood vessels. By understanding how gut bacteria promote angiogenesis in the gut, it may be possible to identify compounds and targets that are useful for treating illnesses that affect the gut, Gordon said.

"We should turn within and look at the microbes we live with," the St. Louis researcher said.

SOURCE: Proceedings of the National Academy of Sciences Early Edition 2002;10.1073/pnas.202604299.

Reprinted from:
http://www.reuters.com

Related
News
SARS ANTHRAX WEST NILE SMALLPOX FLU AIDS THE COMMON COLD  May 04 2003
The Most Interesting Stories from CureZone  Apr 18 2003
Liver Flush - Quackery or Valuable Remedy  Apr 18 2003
Astrology and Health  Jan 24 2003
The Remarkable Raspberry  Dec 08 2002
What is Maggot Therapy?  Nov 22 2002
Bacteria Promote Vessel Growth in Gut  Nov 06 2002
Schools Teach 3 C's: Candy, Cookies and Chips  Sep 25 2002
The Grisanti Report  Aug 30 2002
What Every Hypothyroid Patient Should Know about Synthroid  Aug 30 2002
HOW TO LOWER YOUR CHOLESTEROL  Aug 30 2002
MAGNESIUM DEFICIENCY & SUDDEN DEATH  Aug 30 2002
Autism 'Linked to Mercury Vaccine'  Aug 16 2002
Autism and Mercury  Aug 16 2002
Vitamin E for Your Brain  Aug 09 2002
The cruelty of sucking gallbladder juice (bile) from live bears in China  Jul 23 2002
Bear's Bile - Big Business that may save bears  Jul 23 2002
Tibetan Herbal Medicine, Interview with Dr. Sonam Wangdu Changbhar  Jul 23 2002
Agreement reached to phase out bear farming in China  Jul 23 2002
China's bile bears finding sanctuary  Jul 23 2002
Hospitalization Can Traumatize a Child  Jun 15 2002
THE FRIGHTENING ROAD AHEAD FOR PRESCRIPTION DRUGS  Jun 14 2002
Medical Journal Changes Policy of Finding Independent Doctors to Write  Jun 14 2002
My Personal Experience, Healing Multiple Sclerosis  Jun 10 2002
The Danger of MSG and How it is Hidden in Vaccines  Jun 08 2002
My husband's full recovery from lung tumor and massive heart attack without drugs/chemo/surgery  Jun 07 2002
How I achieved optimum health after a lifetime of suffering  Jun 07 2002
A doctor diagnosed me as having AIDS  Jun 07 2002
New Drugs Same As The Old Drugs?  May 30 2002
Taming the Beast; My Progress - Multiple Sclerosis  May 30 2002
Beating Multiple Sclerosis  May 29 2002
Hospital Drug-Error Trends Continue  May 29 2002
This is what you will bring into your life  May 29 2002
12 Plants that have no purpose  May 26 2002
Pesticides and the Immune System: The Public Health Risks  May 23 2002
Experiments Strengthen Link Between Fish Oil, Mental Problems  May 21 2002
Raw Eating - A book by A.T. Hovannessian (Aterhov)  May 21 2002
POISON FOR PROFIT - WHAT A BUSINESS PLAN!  May 16 2002
The Truth is Out There   May 16 2002
Why Do Pharmaceutical Drugs Injure and Kill?  May 15 2002
Are Vaccines Causing More Disease Than They are Curing?  May 15 2002
Fluoride and Aluminum - toxic combination of fluoroaluminum complex   May 15 2002
The Nocebo Effect: Placebo's Evil Twin  May 15 2002
A Chronology of Fluoridation  May 08 2002
Avoiding Wheat and Gluten May Reverse Liver Failure and Hepatitis  May 08 2002
Fish Oil Helps Prevent Diabetes  May 08 2002
HYPERTHERMIA - The "COLD SHEET" Treatment   May 05 2002
Ailments & Herbal remedies - Dr. Richard Schulze  May 04 2002
Incurables Program - Dr. Richard Schulze  May 04 2002
Herbal Formulas - Dr. Richard Schulze  May 04 2002
Patient Handbook - Dr. Richard Schulze  May 04 2002
HEALTHY WEB LINKS  May 03 2002
Excitotoxins - MSG and Aspartame  May 03 2002
Crib Death - Infection May Cause SIDS  May 02 2002
Exercise Can Lower Risk of Death from Stroke  May 01 2002
Safety of New Drugs Cannot Be Known for Many Years  May 01 2002
Mercury fillings are affecting dentists  May 01 2002
British group says patients can refuse treatment  Apr 30 2002
Minnesota - the first US State to offer Freedom of Choice  Apr 30 2002
The Signs of Inner Peace  Apr 30 2002
WHO announces urgent meeting on new food cancer scare  Apr 29 2002
Few Antispasmodic & Antiinflammatory Herbs  Apr 26 2002
A Simple Guide To Herbs  Apr 26 2002
Diet, Aging, and Muscle by Joe Friel  Apr 26 2002
Akrylamid-listen  Apr 26 2002
Kreftalarm etter giftfunn i mat  Apr 26 2002
Cooked tomatoes 'better for you than raw'  Apr 26 2002
Cancer expert exposes sunbed 'danger'  Apr 26 2002
Angry Young Men At Greater Risk Of Heart Disease  Apr 26 2002
'Programmed Obesity' Handed Down To Next Generation  Apr 26 2002
Understanding the Healing Crisis  Apr 25 2002
Cancer Risk Found in French Fries, Bread   Apr 24 2002
First 20 Years in Life Key to Cancer Risk  Apr 24 2002
Make-Up Holds Hidden Danger of Cancer  Apr 24 2002
Virgin Olive Oil May Reduce Cholesterol Damage  Apr 24 2002
Fish Oil Cuts Risk of Sudden Death  Apr 24 2002

Back To Top


 

Donate to CureZone

Contact Us - About - Sponsors - Stats

Link Exchange - Add URL - How To Exchange Links?

Terms of Service - Privacy Policy - Spam Policy - Disclaimer - Guidelines & Rules

CureZone Newsletter is distributed in partnership with https:www.netatlantic.com


Copyright 2021  www.curezone.com

0.2344 sec from 3.236.23.193