Ahhh as an Artist myself, I think it has more to do with wrestling with the muse than anything else. Sometimes a little, or a lot of chaos before the bliss of creating is the needed fuel to get the fire of imagination going.
In my own personal experience my art is a direct product of the adversity and contrast in my life! I think the creativity is always there, brewing, waiting. I’ve had very long painful spells where I didn’t paint, (within the last 10 years of AF plus…) I didn’t really know it at the time, but I was simply getting prepared to create, and then…the flood gates opened!
Even if one is physically too weak to create, no one can take away the imagination, and it’s the imagination that creates worlds. 5 yrs ago I laid there in my hospital bed getting my 2nd blood transfusion within a week and asked the nurse to "please bring me a piece of paper or I’ll have to draw on the sheets." I just had to write out and sketch an idea that was running in my head for a future painting.
I'm not sure any hormones need to be in place, I don't know anything about that, but I was just about dead back then and ideas were coming to me.
I'm 50 now and painting is pretty much what I breath for.
Never give up, it’s all still in you. So go create :)