I don't think there is anyy particular sequence, although I believe that the best foundation lies in balancing the intestinal flora first and so would recommend the Candida Plan first. I usually follow that with the Parasites and Heavy metal cleanses. Each of these helps to improve the function of the rest of the organs and individual detoxes can be done from there. If someone had a bloodborne parasite infection, I may knock that back first for a couple of weeks, then start the candida Plan. After the Candida Plan, I would then go back to the Parasite cleanse. The idea would never be to eliminate all parasites, but to create a balanced system that regulated all the species.