(Type 1 diabetics, my fellow travellers.. START SELENIUM 2-3 months BEFORE strong iodine, and STOCK your shelves with the fat-soluable vits. Iodine
can kick your butt! K2 MK4 up to 6 grams a day can be a real lifesaver..)
Uhm.. where to begin?
This article discusses the issues of how mercuy interferes with insulin activity:
(Diabetes: Causes, Natural Control, & the Mercury/Vaccine Factor B. Windham(Ed) 2011 )
Alongside flouride, mercury (Hg) is one of the most anti-iodine elements out there. I have no information as of yet as to how lead effects Iodine
status in the body. Hg toxicity pushes (this may not be a complete list) magnesium, zinc, copper, selenium, iodine, manganese and cobalt (B12) levels very low.
I can say for sure that Lugol's
in high concentrations (30% dilution, 1 drop in water each night) gives night sweats like a /bitch/! I ordered Lugol's
powder (5g) home last year. I was using it together with magnesium citrate and malate, vitamin D3, and my normal levothyroxin/eltroxin/synthroid dose (100mcg), and novorapid insulin via a pump.
The night sweats happened only during high blood sugars (generally above 7.5 mmol/L / 126 mg/dl).
Both immune cell type Th1 and Th2 cytokine responses are involved in autoimmunity(425c). Mercury has been found to affect both Th1 and Th2 cytokines causing an increase in inflammatory Th2 cytokines(152,181,285,404b) as well as in Th1 cytokines in some circumstances(6). In the pancreas, the cells responsible for insulin production can be damaged or destroyed by the chronic high levels of cytokines, with the potential of inducing type I or II diabetes - even in otherwise healthy individuals with no other risk factors for diabetes(502). Mercury inhibits production of insulin and is a factor in diabetes and hypoglycemia, with significant reductions in insulin need after replacement of Amalgam
filings and normalizing of blood sugar(35,502). Mercury exposure also increases insulin resistance(505).
" ((Diabetes: Causes, Natural Control, ...)
Mercury exposure causes an approximately 1.8-fold increase in glucose transport. This glucose transport corresponds with an increase in GLUT 1 glucose transporters. Phosphorylation of p38 kinase increased with mercury exposure. Activation of p38 and an increase in glucose transport corresponding to an increase in GLUT 1 are indicative the induction of a stress response, which can contribute to the induction of insulin resistance in adipocytes.
" ((Diabetes: Causes, Natural Control, ...)
GLT-1 is one of the major triggers of insulin production- it's created in the small intestine lining, flows up the bloodtream to the liver and pancreas, and triggers insulin secretion during digestion. IMO, an overrun of GLT-1 is definately going to stress out beta cells (insulin secretors).
"Studies have also found evidence of a connection between low levels of zinc and childhood-onset diabetes(72) . Zinc is an antagonist to toxic metals like cadmium and mercury, and adequate levels are required to balance the adverse effects of these toxic metals on cellular calcium and other enzymatic processes(28,74). Mercury reduces the bloods ability to transport essential nutrients such as calcium, magnesium, and zinc; and has an adverse effect on cellular levels of these essential minerals, as well as blocking the function of magnesium and zinc in cellular enzymatic functions(43,96,198,338). Part of the toxic effects of mercury, cadmium, lead, etc. are through their replacing essential minerals such as zinc at their sites in enzymes, disabling the necessary enzymatic processes. Other connections between mercury and type 1 diabetes have also been demonstrated. Mercury inhibits production of insulin and is a factor in diabetes and hypoglycemia, with significant reductions in insulin need after replacement of Amalgam
filings and normalizing of blood sugar(35)." ((Diabetes: Causes, Natural Control, ...)
Now.. the above article I've quoted doesn't contain the word Iodi(ne/de), and I haven't come across much material yet bringing in information about how iodine/dide deficiency is interrelated with insulin production. Perhaps that's an area you can help me hunt down some connections, Trapper?
And YES, I am very interested in switching from synthroid (levothyroxine) to a proper thyroid extract, but I do lack information. I'm in Denmark, and the language barrier (different names for the products involved) adds a few more levels of complexity to the game.
After starting studies up here in denmarkia (finally got my citizenship and a study income), I've had more flexibility in the supplements and foods I am able to use and try, so a lot has changed since I first went after lugol's.
I have 2 of 13 Amalgams
left in my mouth
I have one root canal
left (the other two broke, owowow, but they are blessedly gone)
I feel my best when using high levels of EFA (omega 3) each day (I'm a fan of Oil Pulling), and I find:
b-complex and lithium orotate induces a sort of mania, but a very high level of seretonin activity, and really dries out the skin (Have dropped both products)
Magnesium Taurate (50-100 mg/day) very much helps a level mind and proper sleep
L-optizinc (I use 5mg/day) with copper secabate () helps energy
5-mthf (B9/metafolin/activated folic acid) & B12 (methylcobalamin sublingally only!) actually /helps drop/ blood sugars about 1/2 hour after a meal
As for discussion Iodine
and type 1 diabetes,
I take 3-5 drops of Lugol's
5% dilution in this order:
First I take low doses of two non-yeast formulations of selenium (Se methionine and Methyl Selenocystine),
1/2 hour later, a version of the Liver Flush
(1-3 tblsp high omega-3 oil in fresh-squeezed lemon juice). An egg yolk is extra good in this if I'm home.. (usually it's cold-pressed ecological sunflower seed oil ... any of you know the name of a stone-pressed, non-harsh EVO available here in the EU?)
1/2 hour after the oils, I use the lugol's.
I've done a few days with using transdermal applications, too.
Lugol's 30%, 2 drops in the navel sent my heartbeat up through the roof, and I could feel my thyroid reacting (that was before I diluted down to 5%)
Lugol's 5%, transdermally around the clavicle region, or on the belly, gives a diffuse, more calm boost of morale (seretonin activity, energy, etc throughout the day. (about 10 drops, since I like using almond oil on the skin and the watery lugol's likes absorbing into clothing :P )
I use tiny sprinklets (less than a match-head) of lithium aspartate sometimes with the iodine/dide to ease out the hyperactity after a dose of Lugol's. It takes about 20 minutes or so for Lugol's to give me a buzz, and at one point it was strong enough that my younger sister gave me a small lecture about being annoyingly manic.
I see iodine supplementation to be a necessity, be it type 1 diabetes or something else.. Especially if the person in question hasn't had the wit to switch out their flouride-enriched toothpaste and mouthwash out yet.. (guilty party speaking here..)
Wouldn't it work in part like this, Trapper?
Methylmercury and inflammation helps create a chronic leaky gut
alongside gut dysbiosis (candida overgrowth .. aka, candida survive Hg toxicity better)
both factors deplete minerals and nutrients
upon which the glutathione cycle is dependant
The pancreatic beta cells can be especially vulnerable to methylmercury toxicity
(feel free to correct my tenth-grade anatomy misconceptions here)
The spleen and the liver both drain filtered toxins into the bile ducts, and once glutathione depletion is bad enough, it harasses the pancreas too.
It'd be very interesting to see data about the prevalence of type 1 diabetes in japanese people who live on an oceanic diet of pacific fish and seaweeds (methylmerury in the fish, but high levels of iodides in the kelps and seaweeds).
Ah! Here's one of the threads to look at for data directly on Iodine and Type 1 diabetes
(Posted By Wombat)----------------
Here's info on Iodine and diabetes:
Orthoiodosupplementation in a Primary Care Practice
"In the Type 1 diabetics that we have been following we have noted that if C-peptide is measurable, this would suggest that the individual is making their own insulin. I have been able to help this group of patients to get off insulin or to greatly reduce the amount they need for good glucose control with Iodoral at 4 tablets/day (50 mg). If C-peptide is absent, then we feel there is no insulin being produced and we have not been able to help this particular group of patients to get off their insulin. We have been able to help these patients lower the total amount of insulin needed to control their glucose."
"It was while treating a large 320-pound woman with insulin dependent diabetes that we learned a valuable lesson regarding the role of iodine in hormone receptor function. This woman had come in via the emergency room with a very high random blood Sugar
of 1,380 mg/dl. She was then started on insulin during her hospitalization and was instructed on the use of a home glucometer. She was to use her glucometer two times per day. Two weeks later on her return office visit for a checkup of her insulin dependent diabetes she was informed that during her hospital physical examination she was noted to have FBD. She was recommended to start on 50 mg ofiodine(4 tablets) at that time. One week later she called us requesting to lower the level of insulin due to having problems with hypoglycemia. She was told to continue to drop her insulin levels as long as she was experiencing hypoglycemia and to monitor her blood sugars carefully with her glucometer. Four weeks later during an office visit her glucometer was downloaded to my office computer, which showed her to have an average random blood Sugar
of 98. I praised the patient for her diligent efforts to control her diet and her good work at keeping her sugars under control with the insulin. She then informed me that she had come off her insulin three weeks earlier and had not been taking any medications to lower her blood sugar. When asked what she felt the big change was, she felt that her diabetes was under better control due to the use of iodine. Two years later and 70 pounds
lighter this patient continues to have excellent glucose control on iodine 50 mg per day. We since have done a study of twelve diabetics and in six cases we were able to wean all of these patients off of medications for their diabetes and were able to maintain a hemoglobin A1C of less than 5.8 with the average random blood Sugar
of less than 100. To this date these patients continue to have excellent control of their Type II diabetes. The range of daily iodine intake was from 50 mg to 100 mg per day. All diabetic patients were able to lower the total amount of medications necessary to control their diabetes. Two of the twelve patients were controlled with the use of iodine plus one medication. Two patients have control of diabetes with iodine plus two medications. One patient had control of her diabetes with three medications plus iodine 50 mg. The one insulin dependent diabetic was able to reduce the intake of Lantus insulin from 98 units to 44 units per day within a period of a few weeks."
& Lots more at the link:
I take it iodine is lipophilic? (absorbed by fat cells/loved by fats)
Makes sense that the doses need to be (at least in the beginning) high, since Hg-induced candidiasis is a sign that folk are having trouble metabolizing stuff beyond plain carbohydrates.
I'm going to continue reading, looking forewards to your repl(ie)s. :)
And feel free to correct me here and there, my assumptions are not always correct!