Since I did not inject ivermectin for a while, the bottle is not sterile enough for injection anymore, therefore I tried rectal adminstration of ivermectin today.
The material I prepared is as follows:
1. stomach tube silicon rubber size 16. Somebody on a blog recommend this because it's soft enough to be not hurt yourself and meanwhile hard enough to go through.
The exact one I use is from this link, but I am sure you can find similar one and cheaper one on ebay.
2. 50mL plastic syringe
3. 0.9% NaCl. Some paper suggest an oral suspension solution which is sold in US. But I still did not receive it, so I decide to use low concentration of NaCL. It's important that you use low concentration of NaCl water not the high salt one because you don't want to flush your bowl,but to keep the drug. The high concentration solution stimulates the movement of the bowl.
Make sure you do a No. 2 first in the bathroom before the drug administration.
1. Take 1.5-2mL ivermectin animal solution from bottle with a 50mL syringe. Then pull around 35mL of 0.9% NaCl into the same syringe.
2. Lubricate the tube with cooking oil such as peanut oil etc.
3. Look at the tubing, Notice there are three holes at one end of the tube, make sure you have to push all the three holes into your body, which is about 45 cm.
4. Slowly push the drug into the body with syringe when the body is laying down to one side. keep the tube in the body for 15min to allow absorption, then pull out of the tubing (there will be liquid dripping). Laying down for another 30min.
Results: I personally feel that the result of this method is better than oral dose of moxidectin but still inferior to the ivermection SC injection. However, it is much less painful than ivermectin injection. I don't feel too much discomfort at all during the rectal administration or after that. The tube is pretty thin, and the liquid amount is not a lot to cause discomfort.
1. Am J Trop Med Hyg. 2003 Apr;68(4):453-5.
Case report: Rectal adminstration of ivermectin to a patient with Strongyloides hyperinfection syndrome.
Tarr PE1, Miele PS, Peregoy KS, Smith MA, Neva FA, Lucey DR.
2. Am J Trop Med Hyg. 2010 Oct;83(4):879-83. doi: 10.4269/ajtmh.2010.10-0258.
Non-oral treatment with ivermectin for disseminated strongyloidiasis.
Fusco DN1, Downs JA, Satlin MJ, Pahuja M, Ramos L, Barie PS, Fleckenstein L, Murray HW.