I found the following analysis from the most excellent book about dysbiosis "The Gut Health Protocol" by John G. Herron. If you suffer from yeast infection of the gut, SIFO, SIBO, irritable bowel syndrome, fructose malabsorption, or leaky gut I cannot recommend this book highly enough. You must read it. It is based on science, not wives tales.
Natural “Kill” Supplements Listed by Risk/ Benefit
The following chart lists various “kill” supplements based on a risk/ benefit basis (presented best to worst). I came up with this chart based on a variety of scientific studies (many listed in this section).
1. Cinnamon Oil – VH/ L/ L, @100 µ/ ml #1
2. Clove Oil – VH/ L/ L @300 µ/ ml #1
3. Turmeric (see Chapter 2) - H/ VL/ VL #2
4. Allicin (made from garlic) – VH/ L/ L #2
5. Coconut Oil – M/ L/ VL #2
6. Caprylic Acid - H/ L/ VL #2
7. Ginger M/ L/ L# 2
8. Olive Leaf Extract H/ M/ M #2
9. Pau D’Arco H/ M/ M #2
10. Berberine M/ L-M/ L #2
11. Neem L/ L/ L #2
12. Oregano Oil - L-M/ H/ H #1, #3
13. Grapefruit Seed Extract (GSE) – VH/ VH/ H
14. Nano / Colloidal Silver
– VH / VH / H
KEY: Ratings above are listed as follows:
“Kills Pathogens / Kills Beneficial Bacteria / Risk to GI” VH = Very High
#1 - See PubMed #16430506209, information taken from the full study, as well as from other research studies. Including DOI: 10.1186/ 1472-6882-6-39, and several other studies (some listed below).
#2 - Information compiled from various sources and was not included in the study above. These supplements are not known to overly harm beneficial bacteria or damage the microbiome and are OK to take during the maintenance phase. According to research studies this supplement has been shown to harm pathogenic bacteria.
#3 - Was not included in the full test protocol due to poor effectiveness, therefore no dosing mentioned.
Herron, John. The Gut Health Protocol: A Nutritional Approach To Healing SIBO, Intestinal Candida, GERD, Gastritis, and other Gut Health Issues (Kindle Locations 2388-2395). Eagle Stock Publishing. Kindle Edition.
I just wanted to mention that according to these studies it would be wise to avoid taking oregano oil (unless it is extremely small amounts such as a drop or two), grapefruit seed extract, or Colloidal Silver
because of their damaging effect on beneficial bacteria in the gut. Think about it. The number one cause of dysbiosis is broad spectrum Antibiotics
. Oregano oil, grapefruit seed extract, Colloidal Silver
, (and or course turpentine) are all broad spectrum Antibiotics
. They kill too much and too well. Avoid them.