Hi, I had symptoms of MS while on the Mirena and none before I had it put in (tingling in my hands and feet and lightheadedness). I have had an MRI of my head and neck (both normal) to R/O MS and just had my Mirena removed today....i sooooo hope that that is the reason for these unusual symptoms! I really hope your wife feels better. I know when you replied to my post it made me feel better to know there are others out there who shared the same symptoms. Good luck.