I'm taking Trapper's SSKI and Magnascent, 10 drops a day each. It doesn't make me depressed in the least. I have been running around here so happy lately. It has been great. Everything amuses me and I don't get mad or irritated like I used to. I never felt that way taking the Iodoral tablets. The Iodoral made me feel better physically, but not happy. Trapper's stuff makes me feel good physically and happy emotionally all at the same time. It's unexplainable, but I think it's my body telling me it likes the change!