Fluzonazole is a chemical substance, like any other prescription drug. It in itself does not contain fluoride. Perhaps if a drug manufacturer uses fluoride as an inactive ingredient when making the tablets, capsules, or liquid form then that's another story. However, according to http://www.rxlist.com/diflucan-drug.htm, fluoride is not an ingredient in Diflucan, which is the most commonly prescribed anti fungal pill.
DIFLUCAN tablets contain 50, 100, 150, or 200 mg of fluconazole and the following inactive ingredients: microcrystalline cellulose, dibasic calcium phosphate anhydrous, povidone, croscarmellose sodium, FD&C Red No. 40 aluminum lake dye, and magnesium stearate.
DIFLUCAN for oral suspension contains 350 mg or 1400 mg of fluconazole and the following inactive ingredients: sucrose, sodium citrate dihydrate, citric acid anhydrous, sodium benzoate, titanium dioxide, colloidal silicon dioxide, xanthan gum and natural orange flavor. After reconstitution with 24 mL of distilled water or Purified Water (USP), each mL of reconstituted suspension contains 10 mg or 40 mg of fluconazole.
The drug Biozole is a generic version of Diflucan. It does not contain fluoride as well.