Is it ok if the Periwinkle powder is "cut and sifted"?
If you just want to swallow it rather than extract it then the cut and sifted will have to be ground in to a powder. Otherwise the cut and sifted will have to made in to a tea or tincture.
So Hver, you are ok with supplementing with Vinpocetine tablets but prefer Periwinkle powder as the overall better choice between the two? I just want the strongest and most effective option. Central Sleep apnea has done a number on my mind/brain over the years. I need to get oxygen to my starving brain.
I do prefer herbs as Nature made them in most cases. As I pointed out Nature creates compounds that help act as balancers and plants rarely if ever have one active component. The only reason compounds are isolated and synthesized is the same reason the pharmaceutical companies do this. Money. Naturally occurring compounds are not patentable. But isolating a compound and making a synthetic of it allows it to be patented giving that company somewhat exclusive rights to what is really now nothing more than a drug.
The isolated synthetic is going to be stronger on a gram for gram basis. But you also take less of the isolate. If taking a dose of the herbal more is taken and between the amount of alkaloids and the synergistic effect the results should be the same or stronger. So the biggest difference is convenience and availability.
And both will still dry up the intestines and therefore should be taken with herbs to retain intestinal moisture.