My best attempt was dosing with 60mg of 2% (150 drops) nascent after more than a month of dosing with 60mg of Lugol's. It only took one day for me to fully respect the true charge and power of nascent. I stopped after day three, realizing it was too much of a good thing.
The biggest difference between the two: Lugol's gives this pronounced surge or spike in one large area vs. a more mellow, tapered and prolonged effect throughout with nascent. Perhaps it's similar to the blood Sugar effect of ingesting pure fructose vs. eating whole fruit. I struggle to completely explain it. Though I'll admit to not having fully considered the effect of the grain alcohol vs. an iodide/iodine solution.