I tried Iosol. I am new to Iodine supplementing so I decided to try it based on reviews at a couple of different vitamin houses online. I used it internally for about 6 weeks and then externally off/on at same time. I recently (1week) switched to Lugol's 2% and have upped my dose from 3 drops/2xs per day to 7 drops/2xs per day-working my way towards 50 mg/day.
A comparison of the two-I seem to be getting more noticeable effects from Lugol's. I too experienced less mental acuity/brain fog on Iosol. I am NOT experiencing that with Lugol's. I am definitely getting some stronger detox reactions-for some reason I cannot eat yogurt anymore;0( (mayb all dairy-I have to try to isolate it in my diet further) while taking Lugol's. I did get hot flashes on Iosol for about first 3 nites, none on Lugol's but day 2 I had a really "hot" wave all over my body that went away after an hour or so. It kinda scared me but not enough to stop me. I am breaking out a bit-nothing major. Every time I recognize a possible detox symptom, I try to take a little Sea Salt and that seems to help.
I think, mainly the differences btwn the two, because the Lugol's is stronger and I am at a much higher dose now than I was on Iosol. I am not a scientist, though, so could be because they are just different forms.