Vit C (either Liponano or Quantum) works like a charm when I drink milk/kefir. Without the sufficient calcium in the diet I find it too stimulative. I have no idea why this Vit C and calcium combo is so effective. There must be some correlation between the two. I have read elsewhere that the proper amount of Vitamin C increases bioavailability of calcium, while very high intake of ascorbic acid will eventually put extra demands on calcium stores (bone) to make up calcium loss.