Wow just noticed I have some pruny fingers tips as well. I have had bags under my eyes ever since my cortisol got stuck in the on position. I have many other symptoms besides the ones I listed for collagen loss. But the biggest 2 have been the bags and insomnia. I noticed my bags start going down when my cortisol does. There was a month I got 12 hours of sleep every night. I am also trying to pinpoint the one of many sups I was taking that month that helped along with the sleep.