I am sorry to hear of your friends trauma and the impairments that resulted. I don't know much about ranial sacral work, but this post is making me interested to check it out.
I have had a mild brain injury all my life and found benefit through Neurofeedback. There is research that supports its ability to help restore brain function in stroke and accident victims as well as with adhd. Painless. But takes repetitive treatment until the waves maintain the proper pattern. It is also called EEG Biofeedback by some sources. There are some self application machines that help to train the brain as well. Very exciting stuff.