Re: Get exact dose of Ivermectin horse paste?
I assume you are using the same Bimectin stuff as you said you were using before? If it is the same as mine then it is labeled as 18.7 mg/g Ivermectin and each tube has a total mass of 6.42g of paste and is marked as being for a total of 600kg of (horse!) bodyweight. If you follow the bodyweight markings exactly on the horse paste syringe for your own exact bodyweight (as you have been doing) then you get the correct 0.2 mg/kg bodyweight dose that you need in the ICU protocol!
Don't believe me? Well, here is the maths:
Total mass of Ivermectin in tube = 18.7 ◊ 6.42 = 120 mg
Entire tube is for 600 kg bodyweight, therefore Ivermectin dose per marked kg of bodyweight on scale = 120 ų 600 = 0.2 mg
Here is the recommended Ivermectin dosage as stated on drugs.com for strongyloidiasis:
Usual Adult Dose for Strongyloidiasis:
0.2 mg/kg orally once
In immunocompromised (including HIV) patients, the treatment of strongyloidiasis may be refractory requiring repeated treatment (i.e., every 2 weeks) and suppressive therapy (i.e., once a month), although well-controlled studies are not available. Cure may not be achievable in these patients.
Dosage guidelines based on body weight:
15 to 24 kg: 3 mg orally one time
25 to 35 kg: 6 mg orally one time
36 to 50 kg: 9 mg orally one time
51 to 65 kg: 12 mg orally one time
66 to 79 kg: 15 mg orally one time
80 kg or more: 0.2 mg/kg orally one time
Therefore you are doing it right, but if you actually weigh 55kg but take the Ivermectin at the 50kg mark (10 mg total Ivermectin) then you are getting a dose of 0.18 mg/kg bodyweight which is still within normal dosage recommendations and probably about right for you. If you up that to the 75kg mark (15 mg total Ivermectin) then you'd get a dose of 0.27 mg/kg bodyweight, which is a bit much but will probably do you no harm and be more potent.
You are probably going fine as you are but roughly splitting the difference between 50 and 75 kg (which will give you 12.5 mg Ivermectin total) will prob be easier than trying to get exactly 5 kg. If it were me though and I wanted that little bit of extra potency then I'd probably be too lazy and save myself the hassle and take it at the 75 kg marker (if it doesn't kill you!!!) now and then, while mainly using the 50 kg.