I posted this before and I will post it again. It is cited from the WiKi page.
"Fibroblasts and fibrocytes are two states of the same cells, the former being the activated state, the latter the less active state, concerned with maintenance and tissue metabolism. Currently, there is a tendency to call both forms fibroblasts. The suffix "blast" is used in cellular biology to denote a stem cell or a cell in an activated state of metabolism.
Fibroblasts are morphologically heterogeneous with diverse appearances depending on their location and activity. Though morphologically inconspicuous, ectopically transplanted fibroblasts can often retain positional memory of the location and tissue context where they had previously resided, at least over a few generations. This remarkable behavior may lead to discomfort[clarification needed] in the rare event that they stagnate there excessively."
My theory is: Hyaluronidase turns off the fibroblasts therefore "resetting" their cellular memory. By stopping these cells the hydrocortisone and neomycin don't have to work so hard to penetrate and saturate the area thus eliminating the inflammation/infection. Once the treatment is stopped the fibroblasts will no longer find anything wrong and then reset themselves. Maybe the fibroblasts are the ones that are triggering a possible autoimmune reaction from the body because their actions are irregular when a person has EC.
The treatment has a lot of promise, no matter if it is 500 years old. If it worked in the past then, there is no reason it shouldn't work now, especially if it has been documented in a medical journal.