Just wanted to let everyone know I just went and picked up a six week supply of Sporanox/Itraconazole and Ciclopirox 0.77% cream. Since I picked up my scripts mid afternoon I plan on starting Sporanox tomorrow morning in order to be consist with the dosing, don't want to develop any resistance. I started the Ciclopirox cream just now though. So far I like the texture and applicability much better than Nystatin Triamcinoline Acetonide. The whole idea is to get better penetration with Ciclopirox and hopefully it targets the yeast like it says it does. The molecular mass of Nystatin is just way too large for any sort of topical dermal penetration. I believe it's in the 900 daltons range where as Ciclopirox is only about 200 daltons. The rule of thumb with topical medicines and or any topical application is that it must be under 500 daltons in order to have any penetration. Just thought I'd share my research with everyone!!