I also took Nystatin oral suspension 100,000 units a couple months ago. I cant say I noticed any difference in the lips or internally how I felt. Nystatin is a pretty "weak" drug. It's been prescribed so freakin much that I think most systemic candida infections are not affected by it....or not enough to kill it off, maybe just suppress it. Can't hurt to try though since it's not hard on the liver or kidneys at all because it doesn't get filtered or very little does through the liver and kidneys. It stays in the digestive tract all the way until it is expelled through feces.