I AGREE WITH CUTELION! There is a cause to everything. People exhibit symptoms b/c of some culprit....whether it's their genetic predispositions to metals or whatever. But you really can't go wrong with treating metals b/c atleast you're treating a CAUSE and not an EFFECT of something hidden. Also please don't discount the gut issues....if they progressed enough, you have to keep that in control until you chelate. Otherwise you won't be able to properly detox from the metals and bad bugs.