ICU's protocol sounds really, really hard on the body. I don't doubt it can be very hard on some types of worms, too.
A 600mg dose of prazi had fairly strong physical sensations & liver effects, but it was bearable. A 2400mg dose sounds awful! I would not even want to consider it unless I had absolutely no other choice & was positive of the worm diagnosis, sure of my detox ability & liver function. It does not sound fun.