No, I haven't had the adrenals tested but I can feel then working better as a result of less toxic burden. When my liver was clogged everything was worse, digestion, kidneys, adrenals, breathing, tinnitus you name it. So for me the CEs were a huge help. I have a little theory, the stones are all the toxins, bacteria, dead material encased safely, but the toxins that are floating around freely in your liver are what make you feel really horrible. Gluten usually makes all of this even worse. I may be completely wrong on this one but I always seem to feel better after a CE.