If I were you, I'd use the zapper according to the instructions the first day. You will kill a TON of really easy to kill stuff like bacterial parasites and other small ones. But it will be a LOT of them so your die-off might be interesting. My worst die-off was my first day of use on my first 15 second zap. I learned to do salt loading and I also started taking 100mg of Lugol's every day after my zapping session to minimize die-off. Now I have zero die-off that I can recognize.