All these flushes and cleanses have no actual Science to back them up, do not listen to these people. Your body naturally detoxifies itself, and the only thing it needs is water so keep hydrated.
I have no idea why my lips have peeled since puberty. I do remember manually peeling them, but I think it was just because they were already naturally super dry.
The reason that men describe themselves having it more than women is one simply thing. Lip gloss, lipstick, chapstick... A higher percentage of women use something to moisturize their lips before they even need it than men do.
Until they discover what is causing this condition (some additive that probably exists in someway in everything that peoples mucous membranes are reacting to; PROBABLY) Just keep your lips moisturized, and no one will notice. You can buy a huge stick of 100% Cocoa Butter at Walgreens for 4$ that will last you for a year and has the fewest amount of additives for the price that I have ever seen.
100% cocoa butter keeps the skin on my lips from getting hard, it also doesn't cause blisters from constant use(like every other chapstick that I've used has). If you skip a day or two your lips wont freak out, they just harden up, and peel off the next two days after you have reapplied.
This isn't a cure, no one really knows why it happens to 90% of us.
But using 100% cocoa butter to keep it from crusting up and looking disgusting works for me.....