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The other Castor oil poison - RCA
 
iodinelmnop Views: 665
Published: 6 years ago
 

The other Castor oil poison - RCA


http://ajnp.webs.com/AJNP-19-2014-Singh-final.pdf

Ricinus communis agglutinin

If RCA is injected into the blood, it will cause the red blood cells to
agglutinate and burst by hemolysis


84
One of the main toxic proteins is ricin which is a potent cytotoxin
but a weak
hemagglutinin, whereas the other one RCA (
Ricinus communis
agglutinin) is a weak cytotoxin and a
powerful hemagglutinin
.
86
Ricin works by inactivating the ribosomes present in cells. Due to this the
ribosomes
do not produce proteins. Cells need these proteins to survive and reproduce, so when
ribosomes are inactivated, cells die. The seed poisoning by ingestion
is due to ricin, not RCA,
because RCA does not penetrate the intestinal wall. The RCA does not affect red blood cells (RBCs) unless given intravenously.

If RCA is injected into the blood, it will cause the red blood cells to
agglutinate and burst by hemolysis

--------------------------------------

Ricin notwithstanding, this is all too close for comfort for me at least. I have no idea if manufacturers are testing for RCA content.

People with favism or hemolytic anemia can die from this. This is not a benign lectin.

--because RCA does not penetrate the intestinal wall--

How many times have we heard that catch phrase, only to find out oh wait some people have leaky guts, or that the Science wasn't quite correct after all.

Caveat emptor.




 

 
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