I've been at this a long time, had a period where I was 'relatively' well for a number of years, and then had a crash again. years ago I used many herbs and like you, became worse. this time around, using herbal again, i'm improving, though very slow...the difference this time is i'm supporting drainage way better, I thought I was before but it wasn't enough. I keep up with colon cleaning, no processed foods, alkaline diet, some kidney herbs, daily infrared saunas (key for me)...I start slow with any herb I take, monitor for effect. I have had enough often scary experience with how die off feels compared to what is when health starts slipping away, so I know I can stop it at any time if I need. so far so good. but long way to go!