I was on Difulcan twice this past year. The first time was in November 2006, when I took 150 mg a day for seven days. The second time was in January 2007, when I took 100 mg for 10 days. I took Nystatin in between (500,000 units, four times a day.) I like Nystatin better, although Difulcan was very good in the beginning for "reigning in" a raging yeast infection.