Hi. I am sorry but I am afraid I do not recall my die off symptoms from the probiotic. It was a while ago. However, I can tell you that detoxing in general ups my anxiety level. The antifungals that have bothered my liver include Grapefruit-Seed-Extract (grapefruit seed extract, Olive leaf and Caprylic acid. But, I think in my case it was due to overuse of them too. I took way more than is recommended, and now am paying the price with a liver that doesn't handle much of anything too well at the moment.