Sounds like bad chemical imbalance which includes hormones. You may have a parasitic bacteria--explains systemic symptoms---and of course, with this comes yeast\fungi\microbiota imbalances.
There may be several parasites involved including protozoa. Do you ever experience uncomfortable erections at night? What about scalp itch? These are some of my persistent symptoms, and I have this problem.
I assume you have sensitivity to light, this is due to a type of neurotxin, produced by certain parasites.
In my case, and in many others, the underlying cause is LYME disease, which is just another name for microbes parasitizing your body.
Have you responded to any Antibiotics in the past? Shroom