I've read that some do skip one of the doses on the first day but I never have (I've done over 20). Personally, I'm just not willing to take the chance that it will be less effective or that the one dose will not fully dialate the ducts. I totally understand where you're coming from but the Hulda Clark method works so well I don't want to mess with a good thing. Although I do mix the ES with fresh apple juice instead of water. It goes down a lot easier that way. In the end (no pun intended) only you can decide. Also, I would not recommend skipping one of the day 2 doses.