Cayenne helps cut mucus in the intestines and is also considered a blood cleanser. However you are already getting some of that from the fresh lemon juice. It would be better to do Master-Cleanse without the cayenne if you are that sensitive to it. A little raw apple cider vinegar (like Bragg's brand) may help enhance the cleansing power of the drink. ACV has a good reputation for being a blood purifier and good all around tonic.